Switching from Similac to Enfamil

Switching from Similac to Enfamil


When it comes to your baby’s nutrition, you want the best possible options. For many parents, this means choosing between two leading baby formula brands, Similac and Enfamil. In this article, we will discuss the differences between these brands, and provide a detailed guide on switching from Similac to Enfamil.

Understanding Specialized Baby Formula Brands

While the standard baby formula is suitable for most babies, some may require specialized formulas to address specific nutritional needs or dietary restrictions. Here’s an overview of some common types of specialized formulas:

  1. Hypoallergenic formula: Designed for babies with cow’s milk protein allergies or sensitivities, hypoallergenic formulas contain hydrolyzed proteins that are easier to digest and less likely to cause allergic reactions.
  2. Soy-based formula: Suitable for babies with lactose intolerance or those following a vegetarian or vegan diet, soy-based formulas are made from soy protein and do not contain any cow’s milk proteins.
  3. Lactose-free formula: Formulated for babies with lactose intolerance, lactose-free formulas use alternative carbohydrate sources, such as corn syrup solids or sucrose, instead of lactose.
  4. Added rice starch formula: Designed for babies with reflux or frequent spit-up, these formulas contain added rice starch, which helps to thicken the formula and reduce regurgitation.
  5. Preemie formula: Specifically formulated for premature or low-birth-weight infants, preemie formulas contain higher amounts of calories, protein, and essential nutrients to support growth and development.
  6. Organic formula: Made with organic ingredients, these formulas adhere to strict standards regarding the production, processing, and handling of ingredients, ensuring they are free of pesticides, synthetic fertilizers, and genetically modified organisms (GMOs).

If you suspect your baby requires a specialized formula, consult your pediatrician for guidance and recommendations. It’s essential to choose a formula that meets your baby’s unique nutritional needs, ensuring their optimal growth and development.

Factors to Consider

Before we dive into the differences between Similac and Enfamil, it’s essential to consider factors like your baby’s age, dietary needs, and any potential food allergies, or sensitivities. Always consult your pediatrician before making any changes to your baby’s diet.



Similac is a popular baby formula brand known for its wide range of options catering to various nutritional needs. Some of the popular Similac formulas include Similac Pro, similac Advance, Similac Sensitive, and Similac Alimentum.

Types of Similac Formulas

  1. Standard milk-based formulas
  2. Soy-based formulas
  3. Hypoallergenic formulas
  4. Specialty formulas for specific needs



Enfamil is another well-known baby formula brand, offering a variety of options for different dietary requirements. Some popular Enfamil formulas include Enfamil NeuroPro, Enfamil Gentlease, and Enfamil A.R.

Types of Enfamil Formulas

  1. Standard milk-based formulas
  2. Soy-based formulas
  3. Hypoallergenic formulas
  4. Specialty formulas for specific needs

Breast milk vs. formula

While breast milk is the ideal source of nutrition for babies, sometimes formula feeding becomes necessary due to various reasons. Both Similac and Enfamil strive to create formulas that closely mimic the composition of breast milk to ensure proper nutrition.

Hypoallergenic formula

For babies with cow’s milk protein allergies or sensitivities, hypoallergenic baby formula is available. These formulas contain hydrolyzed proteins, which are broken down into smaller pieces to minimize allergic reactions. Both Similac and Enfamil offer hypoallergenic soy formula options.

Comparing Similac and Enfamil

While both brands provide a wide range of options, their ingredients and formulation can vary. It’s essential to compare their features to determine which brand may be best for your baby.

Formula ingredients

Common ingredients in both Similac and Enfamil formulas include:

  1. Nonfat milk
  2. Whey protein concentrate solids
  3. Lactose
  4. Vegetable oils
  5. Corn syrup solids

However, there may be variations in the composition and ratios of these ingredients depending on the specific formula.

Switching between brands

Switching between baby formula brands should be done cautiously and with your pediatrician’s guidance.

Making the switch

To ensure a smooth transition, it’s crucial to take a gradual approach when switching from Similac to Enfamil. Here’s a step-by-step guide to help you through the process:

  1. Consult your pediatrician: Before making any changes to your baby’s formula, always consult your pediatrician for guidance and recommendations.
  2. Choose the right Enfamil formula: Based on your baby’s needs and your pediatrician’s advice, select an Enfamil formula that best suits your baby.

Introducing new Baby Formula Brands

  1. Gradual introduction: Start by mixing a small amount of the new Enfamil formula with your baby’s current Similac formula. For example, you can begin with a 75% Similac and 25% Enfamil mix.
  2. Monitor your baby: Observe your baby for any signs of discomfort, allergic reactions, or changes in their digestion, such as increased gas, constipation, or diarrhea.
  3. Increase the ratio: If your baby tolerates the new mix well, gradually increase the proportion of Enfamil formula while decreasing the Similac formula. Continue this process until your baby is fully on the new Enfamil formula.

Monitoring your baby

  1. Watch for changes: Keep a close eye on your baby’s feeding habits, weight gain, and overall health during the transition. Any significant changes may indicate that the new formula isn’t suitable for your baby.
  2. Consult your pediatrician: If you have concerns or notice any adverse reactions, contact your pediatrician immediately for guidance.

How Mixing or Switching Between Different Formulas Affects Your Baby

Switching between or mixing different infant formulas can have various effects on your baby, depending on the specific formulas and your baby’s individual needs. Here’s a closer look at how mixing or switching formulas can impact your baby:

  1. Digestive discomfort: Sudden changes in formula can sometimes cause digestive discomfort, including gas, bloating, or constipation, as your baby’s system adjusts to the new ingredients. Gradually transitioning between formulas can help minimize these effects.
  2. Allergic reactions or sensitivities: If your baby has a known allergy or sensitivity to certain ingredients, switching to a formula containing those ingredients can trigger an allergic reaction or worsen existing sensitivities. Consult your pediatrician before making any changes to your baby’s formula, especially if they have a history of allergies or sensitivities.
  3. Nutritional imbalances: Mixing formulas may lead to nutritional imbalances, as each formula is designed to provide specific levels of nutrients. Combining two different formulas might result in too much or too little of certain nutrients, which can impact your baby’s growth and development. It’s best to stick with one formula unless advised otherwise by your pediatrician.
  4. Taste and texture differences: Switching between formulas can result in noticeable differences in taste and texture, which may cause your baby to be fussy or refuse the new formula. Gradually transitioning between formulas and offering the new formula at room temperature can help your baby adjust to the changes more easily.
  5. Impact on stool consistency: Different formulas can affect the consistency of your baby’s stool. For example, switching from a cow’s milk-based formula to a soy-based formula may cause temporary changes in stool consistency. Monitor your baby’s bowel movements during the transition and consult your pediatrician if you have concerns.

When considering mixing or switching between different formulas, always consult your pediatrician for guidance. They can help you determine the best approach for your baby and provide recommendations based on your baby’s specific needs and preferences.

Tips for a successful transition

  1. Be patient: It may take a week or two for your baby to fully adjust to the new formula. Be patient and allow your baby time to adapt.
  2. Maintain a consistent feeding schedule: Keeping a consistent feeding schedule will help your baby feel more comfortable during the transition.
  3. Offer comfort: If your baby experiences any discomfort during the switch, provide extra cuddles and soothing techniques to help them feel better.

Additional Tips for Formula Feeding Parents

Besides switching between formulas, there are other aspects of formula feeding that parents should consider to ensure their baby’s well-being. Here are some additional tips:

  1. Proper preparation: Always follow the instructions on the formula packaging to ensure you’re mixing the correct proportions of formula powder and water. Incorrect mixing can lead to over- or under-concentration, which may have negative effects on your baby’s health.
  2. Bottle hygiene: Keep bottles and nipples clean and sterilized to minimize the risk of bacterial contamination. Wash all feeding equipment with hot soapy water, and consider using a sterilizer for added safety.
  3. Water quality: Use clean, safe water to mix the formula. If you have concerns about tap water quality, consider using filtered or bottled water.
  4. Temperature control: Test the temperature of the prepared formula before feeding your baby by placing a few drops on your wrist. The formula should be at body temperature or slightly warmer.
  5. Storage and shelf life: Store unopened formula containers in a cool, dry place, and always check the expiration date before use. Once opened, follow the manufacturer’s guidelines for storage and use.
  6. Discarding leftovers: Do not reuse leftover formula from a previous feeding, as bacteria from your baby’s saliva can contaminate the formula. Discard any unused formula after each feeding.
  7. Solid food introduction: Start introducing solid foods to your baby’s diet around six months of age, in consultation with your pediatrician. Continue to offer formula as a primary source of nutrition until your baby is at least one year old.
  8. Transition to cow’s milk: After your baby’s first birthday, you can gradually introduce cow’s milk into their diet. Consult your pediatrician for guidance on the best approach.
  9. Monitor growth and development: Regularly visit your pediatrician to track your baby’s growth and development, and discuss any concerns regarding their nutrition and overall health.

By following these tips and working closely with your pediatrician, you can provide your baby with the best possible nutrition and ensure their healthy growth and development.

Baby Formula Feeding Myths Debunked

Many misconceptions surround formula feeding, which can create confusion and anxiety for parents. Here, we address some common myths to help you make informed decisions about your baby’s nutrition:

Myth 1: All Baby formulas are the same

While all baby formulas must meet specific nutritional standards, they can differ in terms of ingredients, formulation, and suitability for individual babies. It’s important to research and compare formulas, consult your pediatrician, and choose one that best suits your baby’s needs.

Myth 2: Formula-fed babies don’t bond as well with their parents

Bonding is not solely determined by the type of milk your baby consumes. Parents can create strong emotional connections with their formula-fed babies through regular physical contact, eye contact, and responding to their needs.

Myth 3: Switching between baby formulas is harmful

While it’s ideal to find a formula that suits your baby and stick to it, switching between brands is not necessarily harmful. If you do need to ever switch formulas, make the transition gradually and monitor your baby for any signs of discomfort or intolerance.

Myth 4: You can’t mix breast milk and formula

It’s perfectly safe to mix breast milk ( human milk) and formula, as long as you follow proper preparation guidelines. This combination can be helpful for parents who want to supplement breastfeeding with formula.

Myth 5: Formula-fed babies sleep better

There’s no evidence to suggest that formula-fed babies sleep better than breastfed babies. Sleep patterns vary greatly among individual babies and can be influenced by various factors such as age, developmental stage, and environment.

Myth 6: Formula causes obesity

While some studies suggest a link between formula feeding and a higher risk of obesity, other factors such as genetics, diet, and lifestyle also play significant roles. Parents can help prevent obesity by offering age-appropriate portion sizes and encouraging healthy eating habits as their child grows.

As a parent, it’s essential to stay informed and make choices based on accurate information. By debunking these myths, you can feel more confident about your decisions regarding your baby’s nutrition.

Expert advice

Remember that every baby is different, and what works for one may not work for another. It’s essential to consult with your pediatrician and follow their guidance throughout the switching process.


Switching from Similac to Enfamil can be a smooth process if done gradually and with the proper guidance. Always consult your pediatrician, choose the right Enfamil formula, and monitor your baby closely during the transition. With patience and care, your baby will be able to enjoy the benefits of their new formula in no time.

Understanding the various types of baby formulas and the process of switching from one brand to another can help parents make informed decisions about their baby’s nutrition. Always consult your pediatrician before making changes to your baby’s formula and monitor their progress throughout the transition.

By staying informed and working closely with your pediatrician, you can provide the best possible nutrition for your baby, setting the stage for a healthy and happy future.


  1. Can I switch my baby’s formula without consulting a pediatrician?It’s always best to consult your pediatrician before making any changes to your baby’s formula to ensure their safety and well-being.
  2. How long does it take for a baby to adjust to a new formula?It may take a week or two for your baby to fully adjust to the new formula. Be patient and allow your baby time to adapt.
  3. What are the signs that my baby is not tolerating the new formula well?Signs that your baby may not be tolerating the new formula well include increased gas, constipation, diarrhea, vomiting, or any signs of an allergic reaction such as rash or difficulty breathing. Consult your pediatrician if you have concerns.
  4. Can I switch back to the old formula if my baby doesn’t tolerate the new one? Yes, if your baby doesn’t tolerate the new formula, you can gradually switch back to the old formula. However, consult your pediatrician for guidance.
  5. Are there any differences in the nutritional content of Similac and Enfamil formulas?Both brands strive to provide formulas that closely mimic breast milk’s nutritional content. While there may be variations in ingredients and formulation, both brands offer a range of options to cater to different dietary needs. It’s essential to compare specific formulas and consult your pediatrician to determine the best choice for your baby.
  6. Which is better Similac and Enfamil?There is no definitive answer to which formula is better between Similac and Enfamil, as both brands offer high-quality products that cater to various dietary needs. The best choice depends on your baby’s individual needs and preferences. It’s essential to compare specific formulas, consult your pediatrician, and choose the one that suits your baby best.
  7. How long does it take for a baby to adjust to a formula change?It can take one to two weeks for your baby’s digestive system to adjust to a new formula. During this period, monitor your baby’s progress and consult your pediatrician if you have any concerns or if symptoms persist.
  8. What are the side effects of switching formulas?Switching formulas can lead to temporary side effects such as gas, fussiness, diarrhea, or constipation. These symptoms are usually short-lived and resolve as your baby’s digestive system adapts to the new formula. However, if symptoms persist or worsen, it’s crucial to consult your pediatrician.
  9. Can I just switch my baby’s formula?It’s generally recommended to make a gradual transition when switching formulas to minimize the risk of digestive discomfort. You can start by mixing the old and new formulas in gradually increasing ratios over several days, allowing your baby’s digestive system to adapt to the change. Always consult your pediatrician before making changes to your baby’s formula and monitor their progress during the transition. 



This post is written and edited by Sandy who is a clinical pharmacist with over 20 years of experience specializing in pre-natal and post-natal care.